De Roll's Swiss Regiment of infantry was raised in 1794 by Louis Baron de Roll de Emenholz. It consisted predominantly of Swiss and German soldiers. It was placed on the British establishment in 1802.
De Roll's Regiment fought under Sir Ralph Abercrombie in the Egyptian Campaign of 1801. At the Battle of Alexandria (March 1801) the French were defeated, but Abercrombie was killed. His remains were brought to Malta and interred in Fort St Elmo Valletta. De Roll's Regiment was granted the Battle Honour Egypt (1801) and permitted to bear the Sphinx on its Colours. It served in Sicily and took part in the capture of the Ionian Islands (1810).
The regimental surgeon was J. A. Romheld (appointed surgeon on 22 December 1804). The two assistant surgeons were Assistant Surgeon Wilhelm Heyn (appointed 22 December 1804) and Assistant Surgeon Frederick Herring (appointed 3 July 1806).
De Roll's Regiment was disbanded in Corfu in 1815.